Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758095 | 0.88 | ACACB (0.50) | ACACBLPAR3 | |
| SCHEMBL8729119 | 0.84 | ACACB (0.49) | ACACBITGB3ITGA2BHDAC8ADRB3 | |
| SCHEMBL8729003 | 0.84 | ACACB (0.49) | ACACBITGB3ITGA2BHDAC8ADRB3 | |
| SCHEMBL8732286 | 0.84 | ACACB (0.49) | ACACBITGB3ITGA2BHDAC8ADRB3 | |
| SCHEMBL15764483 | 0.84 | ACACB (0.62) | ACACBITGB3ITGA2B | |
| SCHEMBL8726816 | 0.83 | PPARA (0.47) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8726833 | 0.83 | PPARA (0.47) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8726826 | 0.83 | PPARA (0.47) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8729106 | 0.78 | ADRB3 (0.49) | ACACBITGB3ITGA2BHDAC8ADRB3 | |
| SCHEMBL8729115 | 0.78 | ADRB3 (0.49) | ACACBITGB3ITGA2BHDAC8ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |