Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 9/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726903 | 1.00 | SRD5A1 (0.43) | SRD5A1SRD5A2ARTSHRALDH1A1 | |
| SCHEMBL8726847 | 0.86 | G6PD (0.42) | SRD5A2 | |
| SCHEMBL8726845 | 0.86 | G6PD (0.42) | SRD5A2 | |
| SCHEMBL9113667 | 0.85 | SRD5A1 (0.42) | SRD5A1SRD5A2ARTSHRALDH1A1 | |
| SCHEMBL8726885 | 0.77 | SRD5A2 (0.36) | SRD5A1SRD5A2 | |
| SCHEMBL8724695 | 0.77 | SRD5A1 (0.42) | SRD5A1SRD5A2ARTSHRALDH1A1 | |
| SCHEMBL8926809 | 0.76 | SRD5A1 (0.37) | SRD5A1SRD5A2ARALDH1A1 | |
| SCHEMBL8926954 | 0.76 | SRD5A1 (0.36) | SRD5A1SRD5A2ARALDH1A1 | |
| SCHEMBL8075347 | 0.75 | SHBG (0.51) | SRD5A2ARTSHR | |
| SCHEMBL8075351 | 0.75 | SHBG (0.51) | SRD5A2ARTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710275-A | ENZYME AND HORMONE INHIBITORS | MERCK & CO., INC. (US) | 1998-01-20 | — | — | US | disclosed |