Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726847 | 1.00 | G6PD (0.42) | G6PDSRD5A2AKR1B10AKR1B1GPBAR1 | |
| SCHEMBL8726908 | 0.86 | SRD5A1 (0.43) | SRD5A2 | |
| SCHEMBL8726903 | 0.86 | SRD5A1 (0.43) | SRD5A2 | |
| SCHEMBL8726885 | 0.82 | SRD5A2 (0.36) | G6PDSRD5A2 | |
| SCHEMBL8075347 | 0.80 | SHBG (0.51) | SRD5A2GPBAR1 | |
| SCHEMBL8075351 | 0.80 | SHBG (0.51) | SRD5A2GPBAR1 | |
| SCHEMBL9113840 | 0.78 | GPBAR1 (0.36) | SRD5A2GPBAR1 | |
| SCHEMBL8542467 | 0.76 | GABRA1 (0.41) | SRD5A2GPBAR1 | |
| SCHEMBL8063891 | 0.75 | SRD5A2 (0.36) | SRD5A2 | |
| SCHEMBL9239824 | 0.75 | G6PD (0.37) | G6PDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710275-A | ENZYME AND HORMONE INHIBITORS | MERCK & CO., INC. (US) | 1998-01-20 | — | — | US | disclosed |