Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.47 |
| ▸ | PROC | P04070 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727239 | 0.85 | F2 (0.46) | F2PROCF7TPSAB1 | |
| SCHEMBL8723792 | 0.81 | TPSAB1 (0.46) | F2PROCF10F7TPSAB1 | |
| SCHEMBL7310191 | 0.69 | F2 (0.47) | F2PROCF10F7TPSAB1 | |
| Hydrochloric Acid SCHEMBL7953834 | 0.68 | F2 (0.46) | F2PROCF7TPSAB1PRSS1 | |
| SCHEMBL7050535 | 0.68 | F2 (0.44) | F2PROCTPSAB1 | |
| SCHEMBL7304476 | 0.67 | F2 (0.47) | F2PROCTPSAB1PRSS1PRSS2 | |
| SCHEMBL7400135 | 0.67 | F2 (0.61) | F2PROCF10F7PRSS1 | |
| Hydrochloric Acid SCHEMBL7958396 | 0.67 | F2 (0.60) | F2PROCF10F7PRSS1 | |
| Acetic Acid SCHEMBL6475875 | 0.67 | F2 (0.75) | F2F10 | |
| Hydrochloric Acid SCHEMBL7953102 | 0.67 | F2 (0.47) | F2PROCTPSAB1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1996025426-A9 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | — | 1997-06-12 | — | — | WO | disclosed |
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |