Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.44 |
| ▸ | MASP2 | O00187 | 3/20 | 0.44 |
| ▸ | PROC | P04070 | 4/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727239 | 0.70 | F2 (0.46) | F2PROCTPSAB1 | |
| SCHEMBL8723792 | 0.69 | TPSAB1 (0.46) | F2PROCTPSAB1 | |
| SCHEMBL23479026 | 0.68 | F2 (0.66) | F2MASP2 | |
| SCHEMBL28953166 | 0.68 | F2 (0.66) | F2MASP2 | |
| SCHEMBL8727289 | 0.68 | F2 (0.47) | F2PROCTPSAB1 | |
| SCHEMBL23478619 | 0.66 | F2 (0.65) | F2MASP2 | |
| SCHEMBL28842104 | 0.66 | F2 (0.65) | F2MASP2 | |
| SCHEMBL23454624 | 0.64 | F2 (0.68) | F2MASP2 | |
| SCHEMBL23454620 | 0.64 | F2 (0.68) | F2MASP2 | |
| SCHEMBL23454677 | 0.64 | MASP2 (0.75) | F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773955-B1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-0773955-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1995035309-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |