Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29815598 | 0.89 | PTGS1 (0.49) | PTGS1GSTK1OPRM1OPRD1OPRK1 | |
| SCHEMBL21153033 | 0.86 | PTGS1 (0.48) | PTGS1GSTK1OPRM1OPRD1OPRK1 | |
| SCHEMBL29387981 | 0.86 | PTGS1 (0.47) | PTGS1GSTK1OPRM1OPRD1OPRK1 | |
| SCHEMBL2840621 | 0.85 | FCER2 (0.44) | FCER2SLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL2184368 | 0.84 | PTGS1 (0.46) | PTGS1GSTK1OPRM1OPRD1OPRK1 | |
| SCHEMBL2184371 | 0.84 | PTGS1 (0.46) | PTGS1GSTK1OPRM1OPRD1OPRK1 | |
| SCHEMBL7150981 | 0.81 | MAPT (0.53) | OPRM1OPRD1OPRK1SLC7A5 | |
| SCHEMBL7553789 | 0.81 | MAPT (0.53) | OPRM1OPRD1OPRK1SLC7A5 | |
| SCHEMBL29833638 | 0.79 | ECE1 (0.47) | OPRM1OPRD1OPRK1SLC7A5 | |
| SCHEMBL30661454 | 0.78 | PTGS1 (0.47) | PTGS1GSTK1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840619-A1 | PREVENTION AND TREATMENT OF SEPSIS | OPHIDIAN PHARMACEUTICALS, INC. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996040251-A1 | PREVENTION AND TREATMENT OF SEPSIS | OPHIDIAN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |