Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 7/20 | 0.40 |
| ▸ | FNTB | P49356 | 7/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184368 | 0.97 | PTGS1 (0.46) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL2184371 | 0.97 | PTGS1 (0.46) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL1493227 | 0.87 | PTGS1 (0.55) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL8727805 | 0.86 | PTGS1 (0.43) | PTGS1GSTK1OPRD1OPRM1OPRK1 | |
| SCHEMBL8766612 | 0.84 | TERT (0.49) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL19934772 | 0.82 | PTGS1 (0.43) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL19934630 | 0.82 | PTGS1 (0.43) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL21153867 | 0.82 | PTGS1 (0.43) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL19934741 | 0.82 | PTGS1 (0.43) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL19934870 | 0.82 | PTGS1 (0.43) | PTGS1GSTK1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |