Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 6/20 | 0.39 |
| ▸ | FNTB | P49356 | 6/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184371 | 1.00 | PTGS1 (0.46) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL21153033 | 0.97 | PTGS1 (0.48) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL1493227 | 0.84 | PTGS1 (0.55) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL8727805 | 0.84 | PTGS1 (0.43) | PTGS1GSTK1OPRD1OPRM1OPRK1 | |
| SCHEMBL24723249 | 0.82 | TERT (0.38) | PTGS1GSTK1TERT | |
| SCHEMBL29379571 | 0.82 | PTGS1 (0.47) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL8766612 | 0.81 | TERT (0.49) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL29428730 | 0.81 | PTGS1 (0.47) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL8085271 | 0.80 | TERT (0.39) | PTGS1GSTK1TERT | |
| SCHEMBL4862285 | 0.80 | TERT (0.39) | PTGS1GSTK1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2019-03-07 | — | — | US | disclosed |
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | PTGS1 3605/4885GSTK1 1419/4885FNTA 1561/4885 |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | PTGS1 3605/4885GSTK1 1419/4885FNTA 1561/4885 |
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | PTGS1 3605/4885GSTK1 1419/4885FNTA 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.