Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297822 | 0.89 | CYP3A4 (0.52) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL9303606 | 0.88 | SMN1; SMN2 (0.67) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL9303582 | 0.88 | SMN1; SMN2 (0.67) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL28641990 | 0.88 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1PRSS1ACR | |
| SCHEMBL9736600 | 0.87 | MEN1 (0.49) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL9734037 | 0.87 | MEN1 (0.49) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL9736464 | 0.84 | CYP3A4 (0.47) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL9734980 | 0.84 | CYP3A4 (0.47) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL14016992 | 0.83 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2MEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8913388 | 0.83 | THRB (0.61) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |