Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | ACR | P10323 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303606 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL9297822 | 0.92 | CYP3A4 (0.52) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL8727871 | 0.88 | KMT2A (0.50) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL9734980 | 0.86 | CYP3A4 (0.47) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL9736464 | 0.86 | CYP3A4 (0.47) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL9734037 | 0.86 | MEN1 (0.49) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL9736600 | 0.86 | MEN1 (0.49) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL8913388 | 0.85 | THRB (0.61) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL8913018 | 0.85 | KMT2A (0.56) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 | |
| SCHEMBL9302751 | 0.85 | KMT2A (0.56) | SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |