SCHEMBL8727951

SCHEMBL8727951

CCCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.54
ACE P12821 5/20 0.54
CPA1 P15085 3/20 0.54
ACE2 Q9BYF1 3/20 0.54
MMP2 P08253 1/20 0.51
MMP7 P09237 1/20 0.51
MMP9 P14780 1/20 0.51
MMP12 P39900 1/20 0.51
MMP13 P45452 1/20 0.51
PSMB5 P28074 2/20 0.49
CTSK P43235 1/20 0.49
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
NPY4R P50391 1/20 0.48
GNPAT O15228 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1477244 1.00 MME (0.54) MMEACECPA1ACE2MMP2
SCHEMBL6565110 0.97 GNPAT (0.53) MMEACECPA1ACE2PSMB5
SCHEMBL7033970 0.94 NPY4R (0.57) MMEACECPA1ACE2NPY1R
SCHEMBL9955555 0.93 MME (0.60) MMEACECPA1ACE2MMP2
SCHEMBL9955558 0.93 MME (0.60) MMEACECPA1ACE2MMP2
SCHEMBL8213819 0.91 NPY4R (0.56) MMEACENPY1RNPY2RNPY4R
SCHEMBL8213821 0.91 NPY4R (0.56) MMEACENPY1RNPY2RNPY4R
SCHEMBL23616285 0.89 MME (0.55) MMEACECPA1ACE2MMP2
SCHEMBL2873585 0.89 MME (0.62) MMEACECPA1ACE2MMP2
Phenylalanine SCHEMBL7263675 0.88 FPR1 (0.51) NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1077439-C Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 2002-01-09 CN disclosed
US-5792444-A ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1998-08-11 US disclosed
CN-1141002-A Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 1997-01-22 CN disclosed
EP-0675735-A1 METHOD FOR MODULATING TRANSENDOTHELIAL MIGRATION OF CELLS PROMOTING INFLAMMATION, AND RELATED METHODS OF MEASUREMENT THEREOF THE ROCKEFELLER UNIVERSITY (US) 1995-10-11 EP disclosed
WO-1994015641-A1 METHOD FOR MODULATING TRANSENDOTHELIAL MIGRATION OF CELLS PROMOTING INFLAMMATION, AND RELATED METHODS OF MEASUREMENT THEREOF THE ROCKEFELLER UNIVERSITY (US) 1994-07-21 WO disclosed