Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 6/20 | 0.52 |
| ▸ | CPA1 | P15085 | 3/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | CPA2 | P48052 | 1/20 | 0.51 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873585 | 0.91 | MME (0.62) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL1477244 | 0.89 | MME (0.54) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL8727951 | 0.89 | MME (0.54) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL23616279 | 0.88 | CTSL (0.55) | MMP3 | |
| SCHEMBL23616297 | 0.88 | CTSL (0.55) | MMP3 | |
| N-Formylmethionyl-Leucylphenylalanine SCHEMBL9903983 | 0.88 | FPR1 (0.61) | MMEMMP2MMP7MMP9MMP12 | |
| N-Formylmethionyl-Leucylphenylalanine SCHEMBL17202476 | 0.88 | FPR1 (0.61) | MMEMMP2MMP7MMP9MMP12 | |
| N-Formylmethionyl-Leucylphenylalanine SCHEMBL4592799 | 0.88 | FPR1 (0.61) | MMEMMP2MMP7MMP9MMP12 | |
| N-Formylmethionyl-Leucylphenylalanine SCHEMBL39529 | 0.88 | FPR1 (0.61) | MMEMMP2MMP7MMP9MMP12 | |
| N-Formylmethionyl-Leucylphenylalanine SCHEMBL4969844 | 0.88 | FPR1 (0.61) | MMEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |