SCHEMBL8727965

SCHEMBL8727965

CCCCC(N)C(=O)c1ccccc1CC(C(=O)O)N(C=O)C(=O)C(N)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.35
ANPEP P15144 2/20 0.34
RNPEP Q9H4A4 1/20 0.34
DNPEP Q9ULA0 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
LNPEP Q9UIQ6 1/20 0.33
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSH P09668 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
LTA4H P09960 1/20 0.31
LARS1 Q9P2J5 1/20 0.31
FOLH1 Q04609 1/20 0.31
GPR88 Q9GZN0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154435 0.88 FNTA (0.34) ANPEPRNPEPDNPEP
SCHEMBL8997341 0.80 ANPEP (0.40) ANPEPRNPEPDNPEPLTA4HLARS1
SCHEMBL9387444 0.79 ANPEP (0.39) ANPEPRNPEPDNPEPSLC1A3SLC1A2
SCHEMBL9955563 0.78 ALPI (0.43) CTSKSLC1A3SLC1A2SLC1A1CTSL
SCHEMBL4398840 0.77 ANPEP (0.38) CTSKANPEPRNPEPDNPEPSLC1A3
SCHEMBL27861365 0.77 MMP2 (0.38) ANPEPRNPEPDNPEPCYP2C9CYP2C19
SCHEMBL7999637 0.72 ANPEP (0.51) CTSKANPEPRNPEPDNPEPSLC1A3
SCHEMBL7028776 0.71 ANPEP (0.34) ANPEPRNPEPDNPEPLTA4HLARS1
SCHEMBL27809380 0.70 CAPN1 (0.39) CTSKANPEPRNPEPDNPEPSLC1A3
SCHEMBL16556116 0.69 REN (0.43) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1077439-C Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 2002-01-09 CN disclosed
US-5792444-A ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1998-08-11 US disclosed
CN-1141002-A Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 1997-01-22 CN disclosed