Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387444 | 0.87 | ANPEP (0.39) | ANPEPRNPEPDNPEPLARS1LTA4H | |
| SCHEMBL9440161 | 0.87 | SLC1A5 (0.39) | SLC1A5PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL8727965 | 0.80 | CTSK (0.35) | ANPEPRNPEPDNPEPLARS1LTA4H | |
| SCHEMBL154435 | 0.80 | FNTA (0.34) | ANPEPRNPEPDNPEPMEN1KMT2A | |
| SCHEMBL287362 | 0.74 | PPARG (0.48) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL29045686 | 0.73 | ANPEP (0.41) | ANPEPRNPEPDNPEPLARS1LTA4H | |
| SCHEMBL27305323 | 0.72 | PPARG (0.44) | SLC1A5PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL30534322 | 0.71 | ANPEP (0.56) | ANPEPRNPEPDNPEPLTA4HSLC7A5 | |
| SCHEMBL27926021 | 0.71 | ANPEP (0.56) | ANPEPRNPEPDNPEPLTA4HSLC7A5 | |
| SCHEMBL29379111 | 0.70 | NOS3 (0.59) | SLC1A5PPARGPPARAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570352-B1 | Novel hexapeptide | UNIV WASHINGTON (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0570352-A1 | Novel hexapeptide | WASHINGTON UNIVERSITY (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5225531-A | Ligand binding specificity of the leukocyte response integrin expressed by human neutrophils | WASHINGTON UNIVERSITY (US) | 1993-07-06 | — | — | US | disclosed |