Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725719 | 0.93 | PPARD (0.48) | THRBMAPTL3MBTL1HPGDTHRA | |
| SCHEMBL8729402 | 0.86 | THRB (0.46) | THRBMAPTL3MBTL1HPGDATM | |
| SCHEMBL8075449 | 0.85 | MAPT (0.43) | THRBMAPTL3MBTL1HPGDTSHR | |
| SCHEMBL8727988 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL8728340 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL8728094 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL8727990 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL8724440 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL8728244 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E | |
| SCHEMBL8725675 | 0.83 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |