SCHEMBL8728266

SCHEMBL8728266

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nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.62
ACE P12821 3/20 0.62
CPA1 P15085 2/20 0.62
ACE2 Q9BYF1 2/20 0.62
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
PTGS2 P35354 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TERT O14746 1/20 0.49
ECE1 P42892 1/20 0.46
DPP4 P27487 4/20 0.40
DPP8 Q6V1X1 3/20 0.40
DPP9 Q86TI2 3/20 0.40
MMP2 P08253 1/20 0.37
EGLN1 Q9GZT9 2/20 0.36
DPP7 Q9UHL4 2/20 0.36
PTGS1 P23219 1/20 0.36
GSTK1 Q9Y2Q3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10338209 1.00 MME (0.62) MMEACECPA1ACE2ALDH1A1
SCHEMBL8728265 1.00 MME (0.62) MMEACECPA1ACE2ALDH1A1
SCHEMBL30052810 0.93 MME (0.56) MMEACECPA1ACE2ALDH1A1
SCHEMBL30051655 0.88 MME (0.54) MMEACECPA1ACE2ALDH1A1
SCHEMBL30051352 0.87 MME (0.53) MMEACECPA1ACE2ALDH1A1
SCHEMBL30051565 0.85 MME (0.51) MMEACECPA1ACE2ALDH1A1
SCHEMBL26255783 0.85 TERT (0.49) MMEACECPA1ACE2TERT
SCHEMBL30455467 0.84 MME (0.50) MMEACECPA1ACE2ALDH1A1
SCHEMBL30053138 0.83 MME (0.49) MMEACECPA1ACE2ALDH1A1
SCHEMBL12259750 0.82 TERT (0.46) MMEACECPA1ACE2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709912-A1 PROTEIN THERAPEUTICS FOR TREATMENT OF SENESCENT CELLS BioAtla, Inc. (US) 2026-03-18 EP claimed
US-12285037-B2 Flavor composition and edible compositions containing same MARS, INCORPORATED (US) 2025-04-29 US claimed
WO-2024232976-A1 PROTEIN THERAPEUTICS FOR TREATMENT OF SENESCENT CELLS BIOATLA, INC. (US) 2024-11-14 WO claimed
EP-4424365-A2 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2024-09-04 EP claimed
US-20240287509-A1 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (CN) 2024-08-29 US claimed
EP-4017281-B1 PET FOOD COMPOSITIONS HILLS PET NUTRITION INC (US) 2024-08-28 EP claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF Endomimetics LLC 2024-06-20 US claimed
US-20240044046-A1 PROTEIN THERAPEUTICS FOR TREATMENT OF SENESCENT CELLS BIOATLA, INC. (US) 2024-02-08 US claimed
US-11892458-B2 Biochemical predictors of red blood cell quality BLOODWORKS NW (US) 2024-02-06 US claimed
US-11351264-B2 PAR2 mimetic peptides and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-06-07 US claimed
CN-114269768-A Peptide for improving memory and preventing or improving cognitive dysfunction, composition comprising the same, and preparation method thereof 纳特恩斯株式会社 2022-04-01 CN claimed
WO-2021127701-A1 PET FOOD COMPOSITIONS HILL'S PET NUTRITION, INC. (US) 2021-06-24 WO claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 US claimed
US-20210055313-A1 BIOCHEMICAL PREDICTORS OF RED BLOOD CELL QUALITY BLOODWORKS (US) 2021-02-25 US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 US claimed
US-10830777-B2 Biochemical predictors of red blood cell quality BLOODWORKS (US) 2020-11-10 US claimed
EP-3565846-A1 PROTEIN THERAPEUTICS FOR TREATMENT OF SENESCENT CELLS Bioatla, LLC (US) 2019-11-13 EP claimed
WO-2018129007-A1 PROTEIN THERAPEUTICS FOR TREATMENT OF SENESCENT CELLS BIOATLA LLC (US) 2018-07-12 WO claimed
US-20170067884-A1 Method for the Early Detection of Autism Spectrum Disorder by use of Metabolic Biomarkers GREENWOOD GENETIC CENTER 2017-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11351264-B2 PAR2 mimetic peptides and uses thereof F2RL1, F2R, F2RL3 MME 166/4885ACE 710/4885CPA1 175/4885
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF PLD4, NGLY1, VIP MME 274/4885ACE 1225/4885CPA1 1124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.