SCHEMBL8728432

SCHEMBL8728432

C=Cc1cc(F)c(F)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TUBB1 Q9H4B7 2/20 0.38
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
TSHR P16473 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
TRPA1 O75762 1/20 0.34
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23837094 0.83 TP53 (0.35) ALDH1A1TUBB1HDAC8TRPA1TP53
SCHEMBL18840600 0.83 TUBB1 (0.40) ALDH1A1TUBB1CES2CES1TRPA1
SCHEMBL16956527 0.80 ALDH1A1 (0.38) ALDH1A1TSHRHDAC8TP53TDP1
SCHEMBL3214111 0.78 ERN1 (0.37) ALDH1A1TSHRHDAC8TRPA1
SCHEMBL14194018 0.78 ALDH1A1 (0.36) ALDH1A1TSHRHDAC8TP53TDP1
SCHEMBL22688636 0.78 TP53 (0.39) ALDH1A1TUBB1TSHRHDAC8TP53
SCHEMBL1474124 0.74 HDAC8 (0.34) ALDH1A1HDAC8TP53TDP1
SCHEMBL20388755 0.74 ALDH1A1 (0.33) ALDH1A1HDAC8TDP1
SCHEMBL26348258 0.74 TRPA1 (0.35) ALDH1A1TUBB1TSHRTRPA1TP53
SCHEMBL13412052 0.73 FEN1 (0.39) ALDH1A1TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118895034-A Nano-modified pressure-resistant reinforced epoxy glass fiber composite material with fluorine conjugated structure 西安交通大学 2024-11-05 CN claimed
CN-112500513-B Preparation system and process of alpha olefin-fluorostyrene polymer 南京延长反应技术研究院有限公司 2022-12-16 CN claimed
CN-113136001-B Preparation method of ethylene-fluorostyrene copolymer 中国科学院长春应用化学研究所 2022-05-06 CN claimed
CN-113136001-A Preparation method of ethylene-fluorostyrene copolymer 中国科学院长春应用化学研究所 2021-07-20 CN claimed
CN-112500513-A Preparation system and process of alpha olefin-fluorostyrene polymer 南京延长反应技术研究院有限公司 2021-03-16 CN claimed
CN-107722155-B Alpha olefin-fluorostyrene polymer and preparation method thereof 中国科学院长春应用化学研究所 2021-01-08 CN claimed
CN-111892622-A Synthesis method of (3,4, 5-trifluoro phenethyl) -trimethoxy silane 石家庄圣泰化工有限公司 2020-11-06 CN claimed
CN-107722155-A A kind of alhpa olefin fluorobenzene ethene polymer and preparation method thereof 中国科学院长春应用化学研究所 2018-02-23 CN claimed
CN-118895034-A Nano-modified pressure-resistant reinforced epoxy glass fiber composite material with fluorine conjugated structure 西安交通大学 2024-11-05 CN disclosed
EP-4400502-A2 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Shionogi & Co., Ltd (JP) 2024-07-17 EP disclosed
US-12036025-B2 Bio-electrode, method for manufacturing bio-electrode, and method for measuring biological signal SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-16 US disclosed
US-12036025-B2 Bio-electrode, method for manufacturing bio-electrode, and method for measuring biological signal SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-16 US disclosed
US-20240215891-A1 Bio-Electrode Composition, Bio-Electrode, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-20240215890-A1 Bio-Electrode, Bio-Electrode Composition, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
EP-0623102-A1 CYCLOBUTANE-BENZOLE DERIVATIVES MERCK PATENT GmbH (DE) 1994-11-09 EP disclosed
WO-1994012455-A1 CYCLOBUTANE-BENZOLE DERIVATIVES MERCK PATENT GMBH (DE) 1994-06-09 WO disclosed
US-5149743-A Contacting halostyrene monomer with inifer THE UNIVERSITY OF AKRON (US) 1992-09-22 US disclosed
EP-0468041-A4 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF 1992-07-22 EP disclosed
EP-0468041-A1 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF The University of Akron (US) 1992-01-29 EP disclosed
WO-1991012281-A1 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF THE UNIVERSITY OF AKRON (US) 1991-08-22 WO disclosed