SCHEMBL26348258

SCHEMBL26348258

C=Cc1cc(O)c(O)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
ALDH1A1 P00352 2/20 0.34
NFKB1 P19838 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
RGS12 O14924 1/20 0.34
USP2 O75604 1/20 0.34
EGFR P00533 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
LCK P06239 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3214111 0.90 ERN1 (0.37) TRPA1ALDH1A1NFKB1TSHRERN1
SCHEMBL665222 0.85 ALDH1A1 (0.44) TRPA1ALDH1A1NFKB1KDM4EMEN1
SCHEMBL18840600 0.84 TUBB1 (0.40) TRPA1ALDH1A1LCKTUBB1ESR2
SCHEMBL25140015 0.80 PTGS1 (0.47) EGFRCYP3A4CYP2C9ALOX5PTGS1
SCHEMBL19655038 0.80 TRPA1 (0.38) TRPA1NFKB1EGFRLCKCYP3A4
SCHEMBL19655045 0.80 MCL1 (0.42) ALDH1A1NFKB1CYP3A4CYP2C9HPGD
SCHEMBL3689102 0.77 HTR2A (0.35) PTGS1
SCHEMBL30822600 0.76 XDH (0.52) ALDH1A1NFKB1KDM4ESMN1; SMN2ERN1
SCHEMBL1056033 0.76 XDH (0.52) ALDH1A1NFKB1KDM4ESMN1; SMN2ERN1
SCHEMBL26349943 0.76 ALOX5 (0.38) TRPA1ALDH1A1NFKB1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230305398-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed