Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728521 | 0.90 | CA12 (0.49) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL21510393 | 0.85 | KDM4E (0.52) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL21510386 | 0.85 | ADRB2 (0.49) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL8726926 | 0.85 | ADRB2 (0.47) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL9404939 | 0.80 | ADRB2 (0.49) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL9404905 | 0.79 | ADRB2 (0.48) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL9405021 | 0.79 | ADRB2 (0.54) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL9404992 | 0.76 | KDM4E (0.51) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| Hydrochloric Acid SCHEMBL9404892 | 0.75 | LMNA (0.50) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL9751110 | 0.75 | TRPV1 (0.48) | ADRB2ADRA2ADRD2ADRA2CDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335545-B2 | Pharmaceutical formulations for parenteral use | UNIV FLORIDA (US) | 1998-09-23 | — | — | EP | claimed |
| EP-0327766-B1 | Redox systems for brain-targeted drug delivery | UNIV FLORIDA (US) | 1998-04-08 | — | — | EP | claimed |