Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 6/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9404892 | 0.98 | LMNA (0.50) | KDM4EATMTSHRTAAR1MAPK1 | |
| SCHEMBL9751110 | 0.83 | TRPV1 (0.48) | LMNACYP3A4ALDH1A1HIF1AADRB2 | |
| SCHEMBL10483834 | 0.82 | KDM4E (0.56) | KDM4EATMTSHRTAAR1MAPK1 | |
| Oleyl Alcohol SCHEMBL9589663 | 0.81 | LTA4H (0.45) | CYP3A4CYP1A2MEN1KMT2AELANE | |
| Oleyl Alcohol SCHEMBL9589660 | 0.81 | LTA4H (0.45) | CYP3A4CYP1A2MEN1KMT2AELANE | |
| Hydrochloric Acid SCHEMBL16115113 | 0.81 | KDM4E (0.54) | KDM4EATMTSHRTAAR1MAPK1 | |
| Hydrochloric Acid SCHEMBL9586452 | 0.80 | ALOX15 (0.42) | LMNACYP3A4ALDH1A1HIF1ACYP1A2 | |
| SCHEMBL21510393 | 0.80 | KDM4E (0.52) | KDM4ELMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL21510386 | 0.80 | ADRB2 (0.49) | LMNACYP3A4ALDH1A1HIF1AADRB2 | |
| SCHEMBL9404939 | 0.80 | ADRB2 (0.49) | KDM4ELMNACYP3A4ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238124-A1 | ACETYLATED PRODRUGS FOR DELIVERY ACROSS THE BLOOD-BRAIN BARRIER | THE GENERAL HOSPITAL CORPORATION (US) | 2021-08-05 | — | — | US | disclosed |
| WO-2019204808-A1 | ACETYLATED PRODRUGS FOR DELIVERY ACROSS THE BLOOD-BRAIN BARRIER | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-24 | — | — | WO | disclosed |
| EP-0431942-B1 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5296483-A | Antidepressant | UNIVERSITY OF FLORIDA (US) | 1994-03-22 | — | — | US | disclosed |
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| US-5082853-A | Drug delivery | BODOR NICHOLAS S (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4933438-A | Brain-specific analogues of centrally acting amines | UNIVERSITY OF FLORIDA (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0174342-B1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1989-12-20 | — | — | EP | disclosed |
| US-4771059-A | CENTRAL NERVOUS SYSTEM | UNIVERSITY OF FLORIDA (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0174342-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES. | UNIV FLORIDA (US) | 1986-03-19 | — | — | EP | disclosed |
| WO-1985003937-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1985-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238124-A1 | ACETYLATED PRODRUGS FOR DELIVERY ACROSS THE BLOOD-BRAIN BARRIER | AADAC, ACAT2, AANAT | KDM4E 1085/4885ATM 1482/4885TSHR 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.