Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.35 |
| ▸ | THRB | P10828 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 10/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728614 | 1.00 | THRA (0.35) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL8728604 | 1.00 | THRA (0.35) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL7767831 | 0.86 | ITGB3 (0.35) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL7767827 | 0.86 | ITGB3 (0.35) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL7767822 | 0.86 | ITGB3 (0.35) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL7767824 | 0.86 | ITGB3 (0.35) | THRATHRBMEN1KMT2AATG4B | |
| SCHEMBL8731311 | 0.83 | RARB (0.37) | — | |
| SCHEMBL8731307 | 0.83 | RARB (0.37) | — | |
| SCHEMBL8731315 | 0.83 | RARB (0.37) | — | |
| SCHEMBL8727677 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730901-A | Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0742222-A2 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |