Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598103 | 0.79 | KDM4E (0.36) | MEN1KMT2ASIGMAR1GPR3KDM4E | |
| SCHEMBL7066150 | 0.78 | GPR3 (0.31) | GPR3KDM4ELMNATP53CHRM2 | |
| SCHEMBL795334 | 0.76 | HTR6 (0.32) | CYP2D6HTR2A | |
| SCHEMBL8626352 | 0.75 | CYP2D6 (0.35) | POLBGPR3KDM4ELMNATP53 | |
| Hydrochloric Acid SCHEMBL7642128 | 0.72 | SIGMAR1 (0.33) | MEN1KMT2ASIGMAR1KDM4EHTR2A | |
| SCHEMBL797549 | 0.71 | BCHE (0.38) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL3685967 | 0.70 | HTR2A (0.38) | MEN1KMT2ASIGMAR1KDM4ELMNA | |
| SCHEMBL6857385 | 0.70 | RET (0.38) | MEN1KMT2ASIGMAR1KDM4ELMNA | |
| SCHEMBL3385276 | 0.70 | HTR2A (0.38) | MEN1KMT2ASIGMAR1KDM4ELMNA | |
| SCHEMBL29480066 | 0.70 | RET (0.38) | MEN1KMT2ASIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0615981-B1 | Supported catalyst system, its preparation and its use in olefin polymerisation | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |