Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22878502 | 0.83 | PABPC1 (0.46) | CARM1PRMT6PABPC1GNAI3GNAO1 | |
| SCHEMBL8728949 | 0.83 | KCNH2 (0.38) | CARM1PRMT6GNAI3GNAO1GNAI1 | |
| SCHEMBL19723131 | 0.80 | KDM1A (0.42) | CARM1PRMT6PABPC1GNAI3GNAO1 | |
| SCHEMBL8724935 | 0.79 | CARM1 (0.41) | CARM1PRMT6PABPC1GNAI3GNAO1 | |
| SCHEMBL2760188 | 0.79 | SMN1; SMN2 (0.42) | CARM1PRMT6KCNH2CCR5EPHX1 | |
| SCHEMBL23986335 | 0.77 | CARM1 (0.36) | CARM1PRMT6GNAI3GNAO1GNAI1 | |
| SCHEMBL18873644 | 0.77 | KDM1A (0.47) | CARM1PRMT6PABPC1GNAI3GNAO1 | |
| SCHEMBL4572196 | 0.76 | DPP7 (0.44) | GNAI3GNAO1GNAI1KCNH2DPP7 | |
| SCHEMBL15806856 | 0.76 | CARM1 (0.36) | CARM1PRMT6PABPC1GNAI3GNAO1 | |
| SCHEMBL16840920 | 0.74 | KDM1A (0.36) | CARM1PRMT6PABPC1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624584-B1 | Piperazine derivatives useful as calmodulin inhibitors | DAIICHI SEIYAKU CO (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5681954-A | HAS CALMODULIN INHIBITORY ACTIVITY; USEFUL IN TREATING DISEASES OF THE CIRCULATORY ORGANS OR IN CEREBRAL REGION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |