Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728962 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAACYP2C9 | |
| SCHEMBL8582483 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAACYP2C9 | |
| SCHEMBL5685534 | 0.74 | CA2 (0.42) | ALDH1A1MEN1KMT2AMAPK1CA12 | |
| SCHEMBL5685527 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AGAAMAPK1 | |
| Butane SCHEMBL3009709 | 0.70 | MMP2 (0.39) | ALDH1A1MEN1KMT2ACYP2C19MAPK1 | |
| SCHEMBL14778735 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AGAACYP2C9 | |
| SCHEMBL28864044 | 0.69 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL971810 | 0.67 | EPHX1 (0.41) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL14779708 | 0.67 | CYP2D6 (0.44) | ALDH1A1MEN1KMT2AGAACYP2C9 | |
| SCHEMBL3149080 | 0.66 | CA2 (0.47) | ALDH1A1MEN1KMT2AGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |