SCHEMBL8729386

SCHEMBL8729386

CCC(C)(N=C=O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17822676 0.83 ALDH1A1 (0.34) ALDH1A1
SCHEMBL27693428 0.82 TSHR (0.32) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL9232871 0.80 FFAR1 (0.35) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL1457220 0.80 TSHR (0.31) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL4907468 0.79 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL28799371 0.79 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL347445 0.77
SCHEMBL27231084 0.77 DGAT1 (0.33) ALDH1A1
SCHEMBL10451501 0.77 MEN1 (0.39) TSHRALDH1A1
SCHEMBL166358 0.75 TSHR (0.38) TSHRALDH1A1CYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230267-B1 FIVE-MEMBERED C-N LINKED ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2018-09-26 EP disclosed
EP-3230267-A1 FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2017-10-18 EP disclosed
WO-2016091857-A1 FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-16 WO disclosed
CN-102753533-B Imidazolidinedione derivatives AUTIFONY THERAPEUTICS LTD 2014-07-30 CN disclosed
CN-101809017-A phthalazinone derivatives ASTRAZENECA AB 2010-08-18 CN disclosed
EP-0816309-A1 Scavenger assisted combinatorial process for preparing libraries of urea and thiourea compounds ELI LILLY AND COMPANY (US) 1998-01-07 EP disclosed