SCHEMBL8729392

SCHEMBL8729392

C=CC(=O)OCCCCCCCCOC(=O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.71
ALDH1A1 P00352 4/20 0.61
TSHR P16473 3/20 0.61
CYP3A4 P08684 1/20 0.61
THRB P10828 1/20 0.55
LMNA P02545 2/20 0.53
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
BCHE P06276 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9647800 1.00 TDP1 (0.71) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL888081 1.00 TDP1 (0.71) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL433209 0.98 TDP1 (0.73) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL434675 0.95 TDP1 (0.68) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL9503942 0.92 TDP1 (0.65) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL434163 0.92 THRB (0.65) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL27812822 0.91 TDP1 (0.58) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL29315939 0.91 TDP1 (0.58) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL29315936 0.89 TDP1 (0.60) TDP1ALDH1A1TSHRCYP3A4THRB
SCHEMBL10869207 0.88 TSHR (0.54) TDP1ALDH1A1TSHRCYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5800733-A Photo cross-linkable liquid crystal derivatives ROLIC AG (CH) 1998-09-01 US disclosed