Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433209 | 0.94 | TDP1 (0.73) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL8729392 | 0.92 | TDP1 (0.71) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL888081 | 0.92 | TDP1 (0.71) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL9647800 | 0.92 | TDP1 (0.71) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL434675 | 0.91 | TDP1 (0.68) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL29315936 | 0.88 | TDP1 (0.60) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| Benzophenone SCHEMBL28534387 | 0.88 | TSHR (0.55) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL434163 | 0.88 | THRB (0.65) | TDP1ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL17734430 | 0.87 | TDP1 (0.85) | TDP1ALDH1A1TSHRLMNAPPARA | |
| SCHEMBL22609158 | 0.87 | THRB (0.66) | ALDH1A1TSHRCYP3A4THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367054-B1 | UV CROSSLINKABLE COMPOSITION BASED ON COPOLYMERS OF ISOAMYL (METH)ACRYLATES | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | claimed |
| US-5026806-A | Hot melt adhesives | BASF AKTIENGESELLSCHAFT (DE) | 1991-06-25 | — | — | US | claimed |