Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548129 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRTRPA1MAPTPOLB | |
| SCHEMBL6548122 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRTRPA1MAPTPOLB | |
| SCHEMBL18241956 | 0.78 | TSHR (0.52) | ALDH1A1TSHRMAPTACHEKDM4E | |
| SCHEMBL7616489 | 0.75 | SMPD2 (0.42) | ALDH1A1KDM4ELMNA | |
| SCHEMBL3246544 | 0.73 | TRPA1 (0.45) | TRPA1TAAR1KDM4ETDP1ADRA2A | |
| SCHEMBL6546760 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRTRPA1MAPTPOLB | |
| SCHEMBL13176252 | 0.71 | TSHR (0.41) | ALDH1A1TSHRMAPTPOLBACHE | |
| SCHEMBL6547512 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TSHRTRPA1MAPTPOLB | |
| SCHEMBL9325711 | 0.69 | TRPA1 (0.50) | ALDH1A1TSHRTRPA1TAAR1KDM4E | |
| SCHEMBL185170 | 0.67 | TRPA1 (0.50) | ALDH1A1TSHRTRPA1TAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |