Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241490 | 0.84 | RORA (0.49) | RORARORCRORBPIK3CGPIK3CD | |
| SCHEMBL6888728 | 0.80 | PIK3CD (0.48) | RORARORCRORBPIK3CGPIK3CD | |
| SCHEMBL4960428 | 0.79 | PIK3CG (0.47) | KDM4ENPC1MAPK1HSD17B10PIK3CG | |
| SCHEMBL9930827 | 0.79 | CCR2 (0.53) | RORARORCRORBKDM4EMAPK1 | |
| SCHEMBL7731227 | 0.77 | PIK3CD (0.47) | RORARORCRORBKDM4ENPC1 | |
| SCHEMBL23497091 | 0.74 | GRM4 (0.43) | RORARORCRORBNPC1RAB9A | |
| SCHEMBL1234114 | 0.73 | KDM4E (0.58) | KDM4ENPC1MAPK1HSD17B10PIK3CG | |
| SCHEMBL1235217 | 0.72 | PIK3CG (0.55) | PIK3CGPIK3CDPIK3CAPIK3CBMEN1 | |
| SCHEMBL10125972 | 0.72 | PIK3CG (0.57) | RORARORCRORBPIK3CGPIK3CD | |
| SCHEMBL4854398 | 0.72 | PIK3CG (0.50) | RORARORCRORBPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |