Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720799 | 0.87 | VCAM1 (0.60) | SMN1; SMN2MAPTVCAM1ALPLLMNA | |
| SCHEMBL1020735 | 0.85 | MAPT (0.55) | SMN1; SMN2MAPTALPLLMNAHPGD | |
| SCHEMBL29430636 | 0.85 | MAPT (0.55) | SMN1; SMN2MAPTALPLLMNAHPGD | |
| SCHEMBL21962198 | 0.85 | PKM (0.74) | MAPTALPLLMNAHPGDPKM | |
| SCHEMBL11264181 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTLMNAPKMNPSR1 | |
| SCHEMBL2565798 | 0.85 | PKM (0.73) | SMN1; SMN2MAPTLMNAPKMNPSR1 | |
| SCHEMBL21081092 | 0.84 | VCAM1 (0.51) | SMN1; SMN2MAPTVCAM1ALPLLMNA | |
| SCHEMBL8065970 | 0.84 | ALPL (0.60) | SMN1; SMN2MAPTALPLLMNAHPGD | |
| SCHEMBL20647826 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTLMNAHPGDPKM | |
| SCHEMBL31401229 | 0.83 | PKM (0.58) | SMN1; SMN2MAPTALPLLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |