Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997219 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| SCHEMBL11265480 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2PKMNPSR1MAPTPOLB | |
| SCHEMBL8729586 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11265185 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| SCHEMBL11264181 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| SCHEMBL2565798 | 0.74 | PKM (0.73) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| SCHEMBL8727390 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| SCHEMBL8727394 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2PKMNPSR1MAPTKMT2A | |
| SCHEMBL20647826 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2PKMNPSR1MAPTL3MBTL1 | |
| SCHEMBL31401229 | 0.73 | PKM (0.58) | SMN1; SMN2PKMNPSR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |