Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997667 | 0.88 | MAPT (0.50) | SMN1; SMN2MAPTTSHRALDH1A1MEN1 | |
| SCHEMBL11265480 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| SCHEMBL11264181 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| SCHEMBL2565798 | 0.81 | PKM (0.73) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| SCHEMBL1421889 | 0.80 | MAPT (0.73) | SMN1; SMN2MAPTTSHRALDH1A1MEN1 | |
| SCHEMBL31401229 | 0.80 | PKM (0.58) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| SCHEMBL8729586 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| SCHEMBL20647826 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL11265185 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTPKMTSHRNPSR1 | |
| SCHEMBL8729647 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTPKMNPSR1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |