Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL10779840 | 0.84 | TSHR (0.58) | TSHRPOLBAOC3CSNK1ETRPA1 | |
| Phenol SCHEMBL4386880 | 0.80 | TDP1 (0.46) | POLBAOC3LMNASLC6A2SLC6A3 | |
| Benzyl Alcohol SCHEMBL3088175 | 0.79 | TSHR (0.70) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL8057636 | 0.79 | TSHR (0.78) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL109525 | 0.79 | TSHR (0.78) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL11807282 | 0.77 | TSHR (0.74) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL4915528 | 0.77 | TSHR (0.74) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL7114015 | 0.77 | TSHR (0.74) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL28108812 | 0.76 | TSHR (0.82) | TSHRTRPA1LTA4HTP53PPARG | |
| Benzyl Alcohol SCHEMBL540993 | 0.76 | TSHR (0.82) | TSHRTRPA1LTA4HTP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229636-B1 | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery | NASTECH PHARMACEUTICAL COMPANY INC. (US) | 2007-06-12 | — | — | US | claimed |
| US-20200317783-A1 | BISPECIFIC ANTIBODY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| US-8883504-B2 | Cell differentiation suppressing agent, method of culturing cells using the same, culture solution, and cultured cell line | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-1997902-B1 | SCREENING METHOD | UNIV HIROSHIMA (JP) | 2013-09-18 | — | — | EP | disclosed |
| US-8329420-B2 | Screening method for a substance that binds to an intracellular region of TLR4 | HIROSHIMA UNIVERSITY (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20120077856-A1 | PHARMACEUTICAL PRODUCT | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-03-29 | — | — | US | disclosed |
| EP-2366389-A1 | Severe sepsis preventive therapeutic agent | Takeda Pharmaceutical Company Limited (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20110184034-A1 | Severe sepsis preventive therapeutic agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-07-28 | — | — | US | disclosed |
| EP-2260869-A2 | Pharmaceutical product | Takeda Pharmaceutical Company Limited (JP) | 2010-12-15 | — | — | EP | disclosed |
| US-20090317833-A1 | Screening Method | HIROSHIMA UNIVERSITY (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090062355-A1 | Pharmaceutical Product | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-03-05 | — | — | US | disclosed |
| EP-2018855-A1 | PHARMACEUTICAL AGENT | Takeda Pharmaceutical Company Limited (JP) | 2009-01-28 | — | — | EP | disclosed |
| EP-2018872-A1 | PHARMACEUTICAL PRODUCT | Takeda Pharmaceutical Company Limited (JP) | 2009-01-28 | — | — | EP | disclosed |
| EP-1997902-A1 | SCREENING METHOD | Hiroshima University (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-20060058288-A1 | Severe sepsis preventive therapeutic agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1495756-A1 | SEVERE SEPSIS PREVENTIVE THERAPEUTIC AGENT | Takeda Chemical Industries, Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-20040009168-A1 | Multidose antibody formulation | PROTEIN DESIGN LABS, INC. | 2004-01-15 | — | — | US | disclosed |
| US-6180621-B1 | ADMINISTERING TO WARM-BLOODED ANIMALS FOR TREATMENT AND PREVENTION OF INFECTIOUS DISEASES CAUSED BY HELICOBACTER PYLORI | SANKYO COMPANY, LIMITED (JP) | 2001-01-30 | — | — | US | disclosed |
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4912215-A | Cyclic structure with a secondary amide in ring | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062355-A1 | Pharmaceutical Product | ATF1, ATF4, TLR8 | TSHR 3079/4885POLB 4373/4885AOC3 4277/4885 |
| US-20060058288-A1 | Severe sepsis preventive therapeutic agent | TLR1, TLR5, TLR4 | TSHR 2785/4885POLB 4084/4885AOC3 3542/4885 |
| US-20110184034-A1 | Severe sepsis preventive therapeutic agent | TLR1, TLR5, TLR4 | TSHR 2755/4885POLB 4122/4885AOC3 3551/4885 |
| US-20120077856-A1 | PHARMACEUTICAL PRODUCT | ATF1, ATF4, TLR8 | TSHR 3079/4885POLB 4373/4885AOC3 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.