Sugi Predict

Sugi Predict / Compounds / Phenol

Phenol

Phenol

SCHEMBL4386880

CCCC(O)Cl.Oc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ GLA P06280 1/20 0.46
▸ CA3 P07451 1/20 0.46
▸ CA4 P22748 1/20 0.46
▸ CA9 Q16790 1/20 0.46
▸ CA14 Q9ULX7 1/20 0.46
▸ AOC3 Q16853 2/20 0.46
▸ ESR1 P03372 7/20 0.39
▸ ESR2 Q92731 2/20 0.39
▸ LMNA P02545 3/20 0.39
▸ CYP19A1 P11511 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ NQO1 P15559 1/20 0.36
▸ POLB P06746 1/20 0.35
▸ MMP3 P08254 1/20 0.34
▸ BCL2L1 Q07817 1/20 0.34
▸ OPRM1 P35372 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL11850258 0.85 TDP1 (0.52) TDP1CA12CA1CA2GLA
Phenol SCHEMBL27462262 0.83 TDP1 (0.50) TDP1CA12CA1CA2GLA
Phenol SCHEMBL7904128 0.83 TDP1 (0.50) TDP1CA12CA1CA2GLA
Sorbic Acid SCHEMBL5954166 0.81 ACHE (0.39) CA12CA1CA2CA3CA4
Benzyl Alcohol SCHEMBL872990 0.80 TSHR (0.54) TDP1AOC3LMNAPOLBSLC6A2
Metacresol SCHEMBL15412135 0.80 ACHE (0.59) CA12CA2CA9CA14LMNA
Paraben SCHEMBL10734563 0.80 CA12 (0.55) TDP1CA12CA1CA2CA3
Phenol SCHEMBL28143546 0.79 TDP1 (0.46) TDP1CA12CA1CA2GLA
Benzoic Acid SCHEMBL5432914 0.79 TSHR (0.52) LMNAPGRSLC6A2SLC6A3
Orthocresol SCHEMBL7639478 0.79 TRPA1 (0.38) AOC3ESR1ESR2HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243602-A1 IMPROVED USE OF CANNABINOIDS IN THE TREATMENT OF ALZHEIMER'S DISEASE Orcosa Inc. (US) 2023-09-20 — — EP disclosed
WO-2022103636-A1 IMPROVED USE OF CANNABINOIDS IN THE TREATMENT OF ALZHEIMER'S DISEASE Orcosa Inc. (US) 2022-05-19 — — WO disclosed
EP-3820460-A1 METHODS FOR REVERSING HIV LATENCY USING BAF COMPLEX MODULATING COMPOUNDS The Board of Trustees of the Leland Stanford Junior University (US) 2021-05-19 — — EP disclosed
WO-2020072602-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS Frequency Therapeutics, Inc. (US) 2020-04-09 — — WO disclosed
EP-3390368-A1 METHODS FOR PREPARING SUBSTITUTED 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE ArQule, Inc. (US) 2018-10-24 — — EP disclosed
US-9950032-B2 Compositions and methods for lung regeneration AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2018-04-24 — — US disclosed
WO-2017106639-A1 METHODS FOR PREPARING SUBSTITUTED 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE ARQULE, INC. (US) 2017-06-22 — — WO disclosed
EP-2968551-A1 FUSION PROTEINS AND METHODS THEREOF The Trustees of Columbia University in the City of New York (US) 2016-01-20 — — EP disclosed
US-20150125490-A1 COMPOSITIONS AND METHODS FOR LUNG REGENERATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2015-05-07 — — US disclosed
WO-2014151734-A1 FUSION PROTEINS AND METHODS THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2014-09-25 — — WO disclosed
WO-2013066802-A2 COMPOSITIONS AND METHODS FOR LUNG REGENERATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2013-05-10 — — WO disclosed
US-7629380-B2 Antitumor agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-12-08 — — US disclosed
EP-1965803-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASE Biomarin Pharmaceutical Inc. (US) 2008-09-10 — — EP disclosed
US-20070286872-A1 Live Attenuated Nidovirus Vaccines VANDERBILT UNIVERSITY (US) 2007-12-13 — — US disclosed
US-20070219174-A1 METHODS OF TREATING CANCER USING HYPOFRACTIONATED RADIATION AND TEXAPHYRINS PHARMACYCLICS, INC. (US) 2007-09-20 — — US disclosed
WO-2007067570-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASE BIOMARIN PHARMACEUTICAL INC. (US) 2007-06-14 — — WO disclosed
US-20070072790-A1 Antitumor agents AF CHEMICALS 2007-03-29 — — US disclosed
EP-1636259-A2 CHEMOKINE-BINDING PROTEIN THAP1, METHODS AND USE THEREOF Endocube SAS (FR) 2006-03-22 — — EP disclosed
US-6855549-B1 Methods and compositions for increasing the infectivity of gene transfer vectors THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-02-15 — — US disclosed
WO-2004111087-A2 CHEMOKIN-BINDING PROTEIN THAP1, METHODS AND USE THEREOF ENDOCUBE SAS (US) 2004-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219174-A1 METHODS OF TREATING CANCER USING HYPOFRACTIONATED RADIATION AND TEXAPHYRINS TEX10, TEX13A, DIS3 TDP1 927/4885CA12 1279/4885CA1 2761/4885
US-20150125490-A1 COMPOSITIONS AND METHODS FOR LUNG REGENERATION CD68, BMP4, S100B TDP1 3819/4885CA12 2543/4885CA1 3275/4885
US-20070072790-A1 Antitumor agents RB1, TP53, FOXM1 TDP1 2666/4885CA12 2048/4885CA1 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.