Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL1764035 | 0.87 | HSD17B10 (0.97) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 | |
| SCHEMBL7587764 | 0.86 | HSD17B10 (1.00) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 | |
| SCHEMBL219618 | 0.86 | HSD17B10 (1.00) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6160546 | 0.85 | HSD17B10 (0.97) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 | |
| SCHEMBL13579947 | 0.77 | HSD17B10 (0.67) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 | |
| SCHEMBL8729938 | 0.75 | HSD17B10 (0.72) | HSD17B10SLC6A9OPRM1OPRD1OPRK1 | |
| SCHEMBL5556794 | 0.75 | HSD17B10 (0.73) | HSD17B10SLC6A9OPRM1OPRD1OPRK1 | |
| SCHEMBL9374624 | 0.74 | HSD17B10 (0.67) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 | |
| SCHEMBL7842659 | 0.74 | HSD17B10 (0.70) | HSD17B10SLC6A9OPRM1OPRD1OPRK1 | |
| SCHEMBL2539061 | 0.73 | OPRM1 (0.77) | HSD17B10SLC6A9SLC18A3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |