Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.97 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.60 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219618 | 0.98 | HSD17B10 (1.00) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7587764 | 0.98 | HSD17B10 (1.00) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6160546 | 0.97 | HSD17B10 (0.97) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| Ammonia Solution, Strong SCHEMBL8729935 | 0.87 | HSD17B10 (0.74) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2539061 | 0.84 | OPRM1 (0.77) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8729938 | 0.84 | HSD17B10 (0.72) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11880961 | 0.83 | HSD17B10 (0.73) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11593274 | 0.83 | HSD17B10 (0.73) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL5556794 | 0.83 | HSD17B10 (0.73) | HSD17B10OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL3068674 | 0.83 | HSD17B10 (0.73) | HSD17B10OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793596-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20190241610-A1 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS, INC. (US) | 2019-08-08 | — | — | US | disclosed |
| US-10138270-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2018-11-27 | — | — | US | disclosed |
| US-20160362450-A1 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS, INC. (US) | 2016-12-15 | — | — | US | disclosed |
| US-9359399-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20150197545-A1 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-8951970-B2 | Synthetic peptide amides for pain | CARA THERAPEUTICS, INC. (US) | 2015-02-10 | — | — | US | disclosed |
| US-8486894-B2 | Synthetic peptide amides and dimeric forms thereof | CARA THERAPEUTICS, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20130012448-A1 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS, INC. (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2064228-B1 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS INC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-8217007-B1 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110118186-A1 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF | CARA THERAPEUTICS, INC. (US) | 2011-05-19 | — | — | US | disclosed |
| US-7727963-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-7713937-B2 | Synthetic peptide amides and dimeric forms thereof | CARA THERAPEUTICS, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-20100075910-A1 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF | CARA THERAPEUTICS, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20090156508-A1 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF | CARA THERAPEUTICS, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| EP-2064228-A2 | SYNTHETIC PEPTIDE AMIDES | Cara Therapeutics, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090075907-A1 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-7402564-B1 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| WO-2008057608-A2 | SYNTHETIC PEPTIDE AMIDES | CARA THERAPEUTICS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10138270-B2 | Synthetic peptide amides | VIP, OPRK1, OPRL1 | HSD17B10 2420/4885OPRL1 3/4885OPRM1 7/4885 |
| US-20150197545-A1 | SYNTHETIC PEPTIDE AMIDES | VIP, OPRK1, OPRL1 | HSD17B10 2420/4885OPRL1 3/4885OPRM1 7/4885 |
| US-20190241610-A1 | SYNTHETIC PEPTIDE AMIDES | OPRK1, OPRL1, OPRD1 | HSD17B10 754/4885OPRL1 2/4885OPRM1 4/4885 |
| US-20100075910-A1 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF | OPRK1, OPRD1, OPRM1 | HSD17B10 2230/4885OPRL1 4/4885OPRM1 3/4885 |
| US-20090156508-A1 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF | OPRK1, OPRM1, OPRL1 | HSD17B10 2571/4885OPRL1 3/4885OPRM1 2/4885 |
| US-20110118186-A1 | SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF | OPRK1, OPRM1, OPRL1 | HSD17B10 2571/4885OPRL1 3/4885OPRM1 2/4885 |
| US-20090075907-A1 | SYNTHETIC PEPTIDE AMIDES | VIP, OPRK1, OPRL1 | HSD17B10 2420/4885OPRL1 3/4885OPRM1 7/4885 |
| US-20160362450-A1 | SYNTHETIC PEPTIDE AMIDES | VIP, OPRK1, OPRL1 | HSD17B10 2420/4885OPRL1 3/4885OPRM1 7/4885 |
| US-20130012448-A1 | SYNTHETIC PEPTIDE AMIDES | VIP, OPRK1, OPRL1 | HSD17B10 2420/4885OPRL1 3/4885OPRM1 7/4885 |
| US-10793596-B2 | Synthetic peptide amides | OPRK1, OPRL1, OPRD1 | HSD17B10 754/4885OPRL1 2/4885OPRM1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.