SCHEMBL8729958

SCHEMBL8729958

COP(=O)(COS(=O)(=O)c1ccccc1C(F)(F)F)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC22A12 Q96S37 6/20 0.35
HSD11B1 P28845 2/20 0.35
F2 P00734 1/20 0.34
MMP7 P09237 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
NFE2L2 Q16236 1/20 0.32
KAT6A Q92794 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732823 0.94 MEN1 (0.38) MEN1KMT2ASLC22A12HSD11B1F2
SCHEMBL8734942 0.91 ALDH1A1 (0.30)
SCHEMBL8729950 0.88 MEN1 (0.35) MEN1KMT2ASLC22A12HSD11B1F2
SCHEMBL8732229 0.85 MEN1 (0.38) MEN1KMT2ASLC22A12HSD11B1F2
SCHEMBL8734997 0.85 CNR2 (0.32) HSD11B1DPP4DPP8DPP9DPP7
SCHEMBL8735678 0.84 ALDH1A1 (0.32) HSD11B1
SCHEMBL8735596 0.84 MEN1 (0.37) MEN1KMT2ASLC22A12HSD11B1F2
SCHEMBL8764523 0.84 MEN1 (0.37) MEN1KMT2ASLC22A12HSD11B1F2
SCHEMBL8732452 0.82 FFAR1 (0.31)
SCHEMBL8764573 0.82 MEN1 (0.34) MEN1KMT2ASLC22A12HSD11B1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed