SCHEMBL8764573

SCHEMBL8764573

COOP(=O)(COS(=O)(=O)c1ccccc1C(F)(F)F)OOC(C)C

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC22A12 Q96S37 6/20 0.33
HSD11B1 P28845 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
F2 P00734 1/20 0.32
MMP7 P09237 1/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
KAT6A Q92794 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764523 0.95 MEN1 (0.37) MEN1KMT2ASLC22A12HSD11B1RXFP1
SCHEMBL8764695 0.89 SLC22A12 (0.34) MEN1KMT2ASLC22A12HSD11B1RXFP1
SCHEMBL8764018 0.85 HSD11B1 (0.36) MEN1KMT2ASLC22A12HSD11B1RXFP1
SCHEMBL8762933 0.84
SCHEMBL8732823 0.83 MEN1 (0.38) MEN1KMT2ASLC22A12HSD11B1RXFP1
SCHEMBL8763812 0.83 MEN1 (0.35) MEN1KMT2ASLC22A12HSD11B1RXFP1
SCHEMBL8763952 0.83 SMN1; SMN2 (0.31)
SCHEMBL8764065 0.82 HSD11B1 (0.33) HSD11B1F2
SCHEMBL8729958 0.82 MEN1 (0.36) MEN1KMT2ASLC22A12HSD11B1RXFP1
SCHEMBL8763833 0.80 KMT2A (0.38) MEN1KMT2ASLC22A12HSD11B1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed