SCHEMBL8735596

SCHEMBL8735596

CCP(=O)(COS(=O)(=O)c1ccccc1C(F)(F)F)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD11B1 P28845 2/20 0.36
SLC22A12 Q96S37 5/20 0.35
F2 P00734 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MMP7 P09237 1/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
KAT6A Q92794 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732455 0.90 ALDH1A1 (0.31) HSD11B1ALDH1A1
SCHEMBL8763812 0.89 MEN1 (0.35) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8732823 0.87 MEN1 (0.38) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8732229 0.86 MEN1 (0.38) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8729950 0.84 MEN1 (0.35) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8729958 0.84 MEN1 (0.36) MEN1KMT2AHSD11B1SLC22A12F2
SCHEMBL8729974 0.83 KDM2B (0.37) SLC22A12F2
SCHEMBL8735044 0.82 FFAR1 (0.32) ALDH1A1
SCHEMBL8730162 0.82 CTSS (0.32) MEN1KMT2A
SCHEMBL8735717 0.82 SLC6A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed