SCHEMBL8730243

SCHEMBL8730243

CCCCCCCCCCS(=O)(=O)NC(CCCCCC)COP(=O)(O)CCCC

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.47
FDPS P14324 4/20 0.40
PLA2G4A P47712 1/20 0.38
CETP P11597 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972402 0.93 PLA2G2A (0.43) PLA2G2AFDPS
SCHEMBL8730244 0.87 PLA2G2A (0.40) PLA2G2AFDPS
SCHEMBL8733228 0.85 CETP (0.52) CETP
SCHEMBL8733471 0.84 PLA2G2A (0.43) PLA2G2AFDPS
SCHEMBL8727555 0.84 PLA2G2A (0.43) PLA2G2AFDPSPLA2G4A
SCHEMBL8972833 0.81 PLA2G2C (0.48) PLA2G2A
SCHEMBL8972694 0.81 CETP (0.50) CETP
SCHEMBL8972562 0.81 CETP (0.50) CETP
SCHEMBL8973335 0.81 CETP (0.50) CETP
SCHEMBL8973228 0.80 LPAR5 (0.45) PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0701561-B1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 MENARINI LAB (ES) 1998-08-19 EP claimed
EP-0701561-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1996-03-20 EP claimed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 WO claimed
EP-0701561-B1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 MENARINI LAB (ES) 1998-08-19 EP disclosed
EP-0701561-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1996-03-20 EP disclosed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 WO disclosed