Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphorylethanolamine SCHEMBL8972363 | 0.85 | LPAR3 (0.42) | PLA2G2APLA2G2D | |
| SCHEMBL8730243 | 0.81 | PLA2G2A (0.47) | PLA2G2A | |
| SCHEMBL8727555 | 0.81 | PLA2G2A (0.43) | PLA2G2A | |
| SCHEMBL8972402 | 0.80 | PLA2G2A (0.43) | PLA2G2A | |
| SCHEMBL8973228 | 0.80 | LPAR5 (0.45) | PLA2G2CPLA2G2A | |
| SCHEMBL8730244 | 0.79 | PLA2G2A (0.40) | PLA2G2A | |
| SCHEMBL8973086 | 0.78 | TLR2 (0.40) | PLA2G2A | |
| SCHEMBL8972054 | 0.76 | CETP (0.40) | PLA2G2A | |
| SCHEMBL8733471 | 0.76 | PLA2G2A (0.43) | PLA2G2A | |
| SCHEMBL8973427 | 0.76 | FDPS (0.42) | PLA2G2CPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | claimed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | claimed |
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | disclosed |