Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | PRKACG | P22612 | 1/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370729 | 0.82 | SIRT2 (0.46) | IMPDH2CYP2A6SIRT2PIM1PRKD3 | |
| SCHEMBL20846135 | 0.81 | CYP2A6 (0.46) | IMPDH2CYP2A6NR4A2TDO2 | |
| SCHEMBL1202543 | 0.80 | IMPDH2 (0.63) | IMPDH2SIRT2PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL56373 | 0.79 | CYP2A6 (1.00) | IMPDH2CYP2A6PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL30782674 | 0.79 | CYP2A6 (1.00) | IMPDH2CYP2A6PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL38654556 | 0.79 | CYP2A6 (1.00) | IMPDH2CYP2A6PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL30786737 | 0.79 | CYP2A6 (1.00) | IMPDH2CYP2A6PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL23630272 | 0.77 | CYP2A6 (0.96) | IMPDH2CYP2A6PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL7432698 | 0.77 | CYP2A6 (0.96) | IMPDH2CYP2A6PIM1PRKD3ABL1 | |
| 3-Formylindole SCHEMBL30234679 | 0.77 | CYP2A6 (0.96) | IMPDH2CYP2A6PIM1PRKD3ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093395-B | Indoline 3, 4-naphthaline ring framework compound, preparation method and application thereof | 青岛农业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115093395-A | Indoline 3, 4-naphthalene ring framework compound, preparation method and application thereof | 青岛农业大学 | 2022-09-23 | — | — | CN | claimed |
| CN-111187220-A | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2020-05-22 | — | — | CN | claimed |
| CN-108329249-A | A kind of method of synthesis of indole -3- benzaldehyde compounds | 盐城锦明药业有限公司 | 2018-07-27 | — | — | CN | claimed |
| CN-102746211-A | Method for preparing substituted indole-3-methanal compound | Shanghai titan chemical co ltd | 2012-10-24 | — | — | CN | claimed |
| CN-102321009-A | Arylhydrazone derivate, preparation method thereof and application in preparing anti-HIV-1 medicines | UNIV NORTHWEST A&F | 2012-01-18 | — | — | CN | claimed |
| CN-115181090-B | New application of indoline 3,4 naphthaline ring skeleton compound and plant bactericide | 青岛农业大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-115093395-B | Indoline 3, 4-naphthaline ring framework compound, preparation method and application thereof | 青岛农业大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115093395-B | Indoline 3, 4-naphthaline ring framework compound, preparation method and application thereof | 青岛农业大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115181090-A | New application of indoline 3, 4-naphthaline ring framework compound and plant bactericide | 青岛农业大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-115093395-A | Indoline 3, 4-naphthalene ring framework compound, preparation method and application thereof | 青岛农业大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-115093395-A | Indoline 3, 4-naphthalene ring framework compound, preparation method and application thereof | 青岛农业大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-111187220-B | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-108329249-A | A kind of method of synthesis of indole -3- benzaldehyde compounds | 盐城锦明药业有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-108329249-A | A kind of method of synthesis of indole -3- benzaldehyde compounds | 盐城锦明药业有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-102746211-A | Method for preparing substituted indole-3-methanal compound | Shanghai titan chemical co ltd | 2012-10-24 | — | — | CN | disclosed |
| CN-102321009-A | Arylhydrazone derivate, preparation method thereof and application in preparing anti-HIV-1 medicines | UNIV NORTHWEST A&F | 2012-01-18 | — | — | CN | disclosed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |