Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730331 | 0.82 | IMPDH2 (0.65) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL1202543 | 0.80 | IMPDH2 (0.63) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL315329 | 0.79 | CYP2A6 (0.64) | IMPDH2CYP2A6ATMALDH1A1LMNA | |
| SCHEMBL22044988 | 0.76 | ATM (0.61) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL29713628 | 0.76 | ATM (0.61) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL14188727 | 0.72 | HSD17B10 (0.55) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL29942046 | 0.72 | HSD17B10 (0.55) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL3291196 | 0.72 | ALDH1A1 (0.53) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL21850038 | 0.72 | ALDH1A1 (0.52) | SIRT2SIRT1IMPDH2NR4A2PRKD3 | |
| SCHEMBL31443273 | 0.72 | IMPDH2 (0.50) | SIRT2SIRT1IMPDH2NR4A2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |