Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106716 | 0.83 | CTNNB1 (0.59) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2847810 | 0.83 | CTNNB1 (0.59) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6576793 | 0.82 | AKR1C2 (0.56) | AKR1C1KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL1646802 | 0.80 | AKR1C1 (0.69) | AKR1C1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL2106717 | 0.79 | CTNNB1 (0.54) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2847807 | 0.79 | CTNNB1 (0.54) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2106712 | 0.79 | CTNNB1 (0.54) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4782537 | 0.75 | CTNNB1 (0.67) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL1798 | 0.75 | CTNNB1 (0.71) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL466194 | 0.75 | CTNNB1 (0.71) | CTNNB1KMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | claimed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | claimed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | claimed |