SCHEMBL1646802

SCHEMBL1646802

O=C(O)C(=Cc1ccccc1)c1ccccc1C(=Cc1ccccc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 3/20 0.69
CYP3A4 P08684 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
AKR1C3 P42330 3/20 0.54
AKR1C2 P52895 3/20 0.49
TRPA1 O75762 1/20 0.49
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
ALDH1A1 P00352 3/20 0.48
POLB P06746 2/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
HTT P42858 2/20 0.48
LMNA P02545 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28994292 0.88 AKR1C1 (0.60) AKR1C1CYP3A4CYP2C9CYP1A2CYP2D6
SCHEMBL27996338 0.86 AKR1C1 (0.58) AKR1C1CYP3A4CYP2C9CYP1A2CYP2D6
SCHEMBL11435631 0.83 CYP1A2 (0.80) AKR1C1CYP3A4CYP2C9CYP1A2CYP2D6
SCHEMBL9094395 0.83 AKR1C1 (0.55) AKR1C1CYP3A4CYP2C9CYP1A2CYP2D6
SCHEMBL29426430 0.83 CYP1A2 (0.80) AKR1C1CYP3A4CYP2C9CYP1A2CYP2D6
SCHEMBL39275 0.82 AKR1C1 (1.00) AKR1C1CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL181529 0.82 AKR1C1 (1.00) AKR1C1CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL290469 0.82 AKR1C1 (1.00) AKR1C1CYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL6576793 0.82 AKR1C2 (0.56) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL8730398 0.80 CTNNB1 (0.56) AKR1C1CYP3A4CYP2C9CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4144416-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER Johnson & Johnson Consumer Inc. (US) 2023-03-08 EP claimed
EP-3349863-B1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2022-01-19 EP claimed
CN-108025197-B Foaming sunscreen compositions containing UV radiation absorbing compounds and superhydrophilic amphiphilic copolymers 强生消费者公司 2021-09-07 CN claimed
CN-108112232-B Sunscreen compositions comprising superhydrophilic amphiphilic copolymers 强生消费者公司 2021-08-10 CN claimed
EP-3349863-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER Johnson & Johnson Consumer Inc. (US) 2018-07-25 EP claimed
EP-3349723-A1 SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS Johnson & Johnson Consumer Inc. (US) 2018-07-25 EP claimed
WO-2017048557-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC. (US) 2017-03-23 WO claimed
US-20170079892-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC. 2017-03-23 US claimed
WO-2017048556-A1 SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS JOHNSON & JOHNSON CONSUMER INC. (US) 2017-03-23 WO claimed
US-20170079893-A1 PHASE-STABLE SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS JOHNSON & JOHNSON CONSUMER INC. 2017-03-23 US claimed
US-8475774-B2 Sunscreen compositions comprising an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-07-02 US claimed
EP-2533860-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER Johnson & Johnson Consumer Companies Inc. (US) 2012-12-19 EP claimed
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC. 2011-08-11 US claimed
WO-2011097555-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES INC. (US) 2011-08-11 WO claimed
EP-4144416-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER Johnson & Johnson Consumer Inc. (US) 2023-03-08 EP disclosed
EP-3349863-B1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2022-01-19 EP disclosed
CN-108025197-B Foaming sunscreen compositions containing UV radiation absorbing compounds and superhydrophilic amphiphilic copolymers 强生消费者公司 2021-09-07 CN disclosed
US-20100129299-A1 TOPICAL SUNSCREEN COMPOSITIONS FOR MITIGATING EFFECTS ON INTRACELLULAR ION CONCENTRATION NEUTROGENA CORPORATION 2010-05-27 US disclosed
US-5698183-A MODIFIED POLYESTER OR POLYAMIDE; SUNSCREEN AGENT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-12-16 US disclosed
US-5250652-A High loading water-dispersible UVA and/or UVB light-absorbing copolymer LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170079893-A1 PHASE-STABLE SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS PCNA, MMS19, SUN2 AKR1C1 2386/4885CYP3A4 2027/4885CYP2C9 1029/4885
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER ERCC1, MMS19, ERCC5 AKR1C1 2724/4885CYP3A4 1092/4885CYP2C9 515/4885
US-20100129299-A1 TOPICAL SUNSCREEN COMPOSITIONS FOR MITIGATING EFFECTS ON INTRACELLULAR ION CONCENTRATION NUDT1, SUN2, SLC29A2 AKR1C1 1538/4885CYP3A4 4486/4885CYP2C9 3048/4885
US-20170079892-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER MMS19, SUN2, PCNA AKR1C1 1600/4885CYP3A4 2046/4885CYP2C9 820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.