Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735074 | 0.86 | POLB (0.50) | POLBTSHRALDH1A1PBRM1FEN1 | |
| SCHEMBL8735186 | 0.82 | ALDH1A1 (0.43) | POLBALDH1A1LMNASLC6A9KDM4E | |
| SCHEMBL8733056 | 0.80 | SLC6A9 (0.44) | POLBTSHRALDH1A1SLC6A9L3MBTL1 | |
| SCHEMBL8732638 | 0.77 | HPGD (0.63) | POLBALDH1A1LMNASLC6A9KDM4E | |
| SCHEMBL27796522 | 0.76 | CA12 (0.55) | POLBTSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27671437 | 0.75 | IRAK4 (0.56) | LMNAKDM4EL3MBTL1IRAK4 | |
| SCHEMBL8761377 | 0.74 | ALDH1A1 (0.41) | TSHRPPARGPPARAALDH1A1LMNA | |
| SCHEMBL8735064 | 0.71 | CA12 (0.48) | POLBTSHRALDH1A1PBRM1FEN1 | |
| SCHEMBL8733055 | 0.71 | ALDH1A1 (0.59) | POLBALDH1A1LMNAFEN1KDM4E | |
| SCHEMBL320037 | 0.71 | ALDH1A1 (0.61) | POLBTSHRALDH1A1LMNAPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749416-B1 | SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO CO (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5482974-A | AMINO OR ETHER BENZAMIDES | MONSANTO COMPANY (US) | 1996-01-09 | — | — | US | disclosed |