Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949387 | 0.88 | ALDH1A1 (0.73) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL27881214 | 0.85 | TSHR (0.70) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| Bicarbonate SCHEMBL5184161 | 0.85 | ALDH1A1 (0.69) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL1073658 | 0.83 | ALDH1A1 (0.71) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11427520 | 0.81 | TSHR (0.73) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL5157954 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL9969538 | 0.80 | TSHR (0.65) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL975212 | 0.80 | TSHR (0.77) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL524955 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL8730957 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |