Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020070 | 0.90 | ALDH1A1 (0.63) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL12909401 | 0.85 | ALDH1A1 (0.74) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11343733 | 0.85 | ALDH1A1 (0.57) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL2949387 | 0.85 | ALDH1A1 (0.73) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL1073658 | 0.83 | ALDH1A1 (0.71) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11329803 | 0.83 | ADRB2 (0.49) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| Bicarbonate SCHEMBL5184161 | 0.82 | ALDH1A1 (0.69) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL27881214 | 0.82 | TSHR (0.70) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL28214366 | 0.82 | TSHR (0.65) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL28020522 | 0.81 | ADRB2 (0.69) | ALDH1A1ADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160000067-A1 | FORMULATIONS | SYNGENTA LIMITED (GB) | 2016-01-07 | — | — | US | claimed |
| US-9807999-B2 | Formulations | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-20160000067-A1 | FORMULATIONS | SYNGENTA LIMITED (GB) | 2016-01-07 | — | — | US | disclosed |
| EP-2598472-B1 | FORMULATIONS | SYNGENTA LTD (GB) | 2015-06-17 | — | — | EP | disclosed |
| EP-2598472-A2 | FORMULATIONS | Syngenta Limited (GB) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014152-A2 | FORMULATIONS | SYNGENTA LIMITED (GB) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000067-A1 | FORMULATIONS | PRMT1, PRMT5, PRMT3 | ALDH1A1 1490/4885ADRB2 951/4885ADRB1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.