Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22320257 | 0.83 | TSHR (0.61) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL7453704 | 0.83 | SLC6A3 (0.51) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL29617021 | 0.82 | TSHR (0.80) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL3683272 | 0.82 | TSHR (0.80) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL10609295 | 0.78 | ALDH1A1 (0.55) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL1452206 | 0.78 | TSHR (0.61) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL9098406 | 0.78 | TSHR (0.61) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL9853783 | 0.77 | TSHR (0.49) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL22320258 | 0.77 | TSHR (0.61) | TSHRHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL1510227 | 0.77 | TSHR (0.56) | TSHRHSD17B10ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |