SCHEMBL8731107

SCHEMBL8731107

C=Cc1ccc(-c2ccc(-c3ccc(COCC=CCC)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
ALOX5 P09917 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
IDO1 P14902 2/20 0.33
AGXT P21549 2/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
KMT2A Q03164 1/20 0.32
TK1 P04183 1/20 0.31
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731104 1.00 ALDH1A1 (0.34) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8732877 0.91 ALOX5 (0.36) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8732883 0.91 ALOX5 (0.36) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8730548 0.86 ALDH1A1 (0.35) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8730544 0.86 ALDH1A1 (0.35) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8727846 0.86 ALDH1A1 (0.35) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8727848 0.86 ALDH1A1 (0.35) ALDH1A1ALOX5CHRNB2CHRNB4CHRNA3
SCHEMBL8727039 0.84 ALDH1A1 (0.42) ALDH1A1ALOX5IDO1AGXTMAPT
SCHEMBL8727041 0.84 ALDH1A1 (0.42) ALDH1A1ALOX5IDO1AGXTMAPT
SCHEMBL8730745 0.84 ALDH1A1 (0.42) ALDH1A1ALOX5IDO1AGXTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed